Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?

Astrocytic dysfunction contributes to the molecular pathogenesis of major depressive disorder (MDD). However, the astrocytic subtype that mainly contributes to MDD etiology and whether dysregulated autophagy in astrocytes is associated with MDD remain unknown. Using a single-nucleus RNA sequencing (...

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Detalles Bibliográficos
Autores principales: He, Shen, Shi, Yue, Ye, Jinmei, Yin, Jiahui, Yang, Yufang, Liu, Dan, Shen, Ting, Zeng, Duan, Zhang, Min, Li, Siyuan, Xu, Feikang, Cai, Yiyun, Zhao, Faming, Li, Huafang, Peng, Daihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673997/
https://www.ncbi.nlm.nih.gov/pubmed/38001115
http://dx.doi.org/10.1038/s41398-023-02665-2

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