Loss of p53 function promotes DNA damage-induced formation of nuclear actin filaments

Tumor suppressor p53 plays a central role in response to DNA damage. DNA-damaging agents modulate nuclear actin dynamics, influencing cell behaviors; however, whether p53 affects the formation of nuclear actin filaments remains unclear. In this study, we found that p53 depletion promoted the formati...

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Detalles Bibliográficos
Autores principales: Torii, Takeru, Sugimoto, Wataru, Itoh, Katsuhiko, Kinoshita, Natsuki, Gessho, Masaya, Goto, Toshiyuki, Uehara, Ikuno, Nakajima, Wataru, Budirahardja, Yemima, Miyoshi, Daisuke, Nishikata, Takahito, Tanaka, Nobuyuki, Hirata, Hiroaki, Kawauchi, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674001/
https://www.ncbi.nlm.nih.gov/pubmed/38001089
http://dx.doi.org/10.1038/s41419-023-06310-0

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