Cargando…

Low-dose radiotherapy of osteoarthritis: from biological findings to clinical effects—challenges for future studies

Osteoarthritis (OA) is one of the most common and socioeconomically relevant diseases, with rising incidence and prevalence especially with regard to an ageing population in the Western world. Over the decades, the scientific perception of OA has shifted from a simple degeneration of cartilage and b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weissmann, Thomas, Rückert, Michael, Putz, Florian, Donaubauer, Anna-Jasmina, Hecht, Markus, Schnellhardt, Sören, Schubert, Philipp, Roesch, Johannes, Höfler, Daniel, Ott, Oliver J., Haderlein, Marlen, Lettmaier, Sebastian, Fietkau, Rainer, Frey, Benjamin, Gaipl, Udo S., Deloch, Lisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674008/ https://www.ncbi.nlm.nih.gov/pubmed/36602569 http://dx.doi.org/10.1007/s00066-022-02038-6

Ejemplares similares

Low-Dose Radiotherapy Leads to a Systemic Anti-Inflammatory Shift in the Pre-Clinical K/BxN Serum Transfer Model and Reduces Osteoarthritic Pain in Patients
por: Weissmann, Thomas, et al.
Publicado: (2022)

Low- vs. high-dose radiotherapy in Graves’ ophthalmopathy: a retrospective comparison of long-term results
por: Weissmann, Thomas, et al.
Publicado: (2021)

The Influence of Radiation on Bone and Bone Cells—Differential Effects on Osteoclasts and Osteoblasts
por: Donaubauer, Anna-Jasmina, et al.
Publicado: (2020)

Low-Dose Radiotherapy Has No Harmful Effects on Key Cells of Healthy Non-Inflamed Joints
por: Deloch, Lisa, et al.
Publicado: (2018)

Combinations of Radiotherapy with Vaccination and Immune Checkpoint Inhibition Differently Affect Primary and Abscopal Tumor Growth and the Tumor Microenvironment
por: Rückert, Michael, et al.
Publicado: (2021)

Low Dose Radiation Therapy, Particularly with 0.5 Gy, Improves Pain in Degenerative Joint Disease of the Fingers: Results of a Retrospective Analysis
por: Donaubauer, Anna-Jasmina, et al.
Publicado: (2020)

Prospective Evaluation of All-lesion Versus Single-lesion Radiotherapy in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors
por: Schubert, Philipp, et al.
Publicado: (2020)

Oligometastatic head and neck cancer: Which patients benefit from radical local treatment of all tumour sites?
por: Weissmann, Thomas, et al.
Publicado: (2021)

Salivary gland carcinoma (SGC) with perineural spread and/or positive resection margin – high locoregional control rates after photon (chemo) radiotherapy - experience from a monocentric analysis
por: Haderlein, Marlen, et al.
Publicado: (2019)

Reduction of Elective Radiotherapy Treatment Volume in Definitive Treatment of Locally Advanced Head and Neck Cancer—Comparison of a Prospective Trial with a Revised Simulated Contouring Approach
por: Weissmann, Thomas, et al.
Publicado: (2021)

Modern Radiotherapy Concepts and the Impact of Radiation on Immune Activation
por: Deloch, Lisa, et al.
Publicado: (2016)

Keine abskopalen Effekte bei Kombination von Immuntherapie und stereotaktischer Radiotherapie bei Merkel-Zell-Karzinomen
por: Schnellhardt, Sören, et al.
Publicado: (2023)

Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose
por: Deloch, Lisa, et al.
Publicado: (2019)

Benchmarking ChatGPT-4 on a radiation oncology in-training exam and Red Journal Gray Zone cases: potentials and challenges for ai-assisted medical education and decision making in radiation oncology
por: Huang, Yixing, et al.
Publicado: (2023)

Deep Learning and Registration-Based Mapping for Analyzing the Distribution of Nodal Metastases in Head and Neck Cancer Cohorts: Informing Optimal Radiotherapy Target Volume Design
por: Weissmann, Thomas, et al.
Publicado: (2023)

Dose Reduction to the Swallowing Apparatus and the Salivary Glands by De-Intensification of Postoperative Radiotherapy in Patients with Head and Neck Cancer: First (Treatment Planning) Results of the Prospective Multicenter DIREKHT Trial
por: Haderlein, Marlen, et al.
Publicado: (2020)

Hypofractionated Radiotherapy Upregulates Several Immune Checkpoint Molecules in Head and Neck Squamous Cell Carcinoma Cells Independently of the HPV Status While ICOS-L Is Upregulated Only on HPV-Positive Cells
por: Wimmer, Sebastian, et al.
Publicado: (2021)

Prospective Evaluation of CD45RA+/CCR7- Effector Memory T (T(EMRA)) Cell Subsets in Patients with Primary and Secondary Brain Tumors during Radiotherapy of the Brain within the Scope of the Prospective Glio-CMV-01 Clinical Trial
por: Scheer, Ilka, et al.
Publicado: (2023)

Deep learning for automatic head and neck lymph node level delineation provides expert-level accuracy
por: Weissmann, Thomas, et al.
Publicado: (2023)

Low Dose Radiation Therapy Induces Long-Lasting Reduction of Pain and Immune Modulations in the Peripheral Blood – Interim Analysis of the IMMO-LDRT01 Trial
por: Donaubauer, Anna-Jasmina, et al.
Publicado: (2021)

Corrigendum: Low Dose Radiation Therapy Induces Long-Lasting Reduction of Pain and Immune Modulations in the Peripheral Blood - Interim Analysis of the IMMO-LDRT01 Trial
por: Donaubauer, Anna-Jasmina, et al.
Publicado: (2022)

Tumor Cell-Based Vaccine Generated With High Hydrostatic Pressure Synergizes With Radiotherapy by Generating a Favorable Anti-tumor Immune Microenvironment
por: Seitz, Christoph, et al.
Publicado: (2019)

Radio-Immunotherapy-Induced Immunogenic Cancer Cells as Basis for Induction of Systemic Anti-Tumor Immune Responses – Pre-Clinical Evidence and Ongoing Clinical Applications
por: Derer, Anja, et al.
Publicado: (2015)

Volumetric Regression in Brain Metastases After Stereotactic Radiotherapy: Time Course, Predictors, and Significance
por: Oft, Dominik, et al.
Publicado: (2021)

The Prognostic Value of FoxP3+ Tumour-Infiltrating Lymphocytes in Rectal Cancer Depends on Immune Phenotypes Defined by CD8+ Cytotoxic T Cell Density
por: Schnellhardt, Sören, et al.
Publicado: (2022)

Clinically Relevant Radiation Exposure Differentially Impacts Forms of Cell Death in Human Cells of the Innate and Adaptive Immune System
por: Falcke, Sylvia E., et al.
Publicado: (2018)

High-grade salivary gland cancer: is surgery followed by radiotherapy an adequate treatment to reach tumor control? Results from a tertiary referral centre focussing on incidence and management of distant metastases
por: Freitag, Viola, et al.
Publicado: (2021)

Prospective development and validation of a liquid immune profile-based signature (LIPS) to predict response of patients with recurrent/metastatic cancer to immune checkpoint inhibitors
por: Zhou, Jian-Guo, et al.
Publicado: (2021)

Targeted Therapy, Chemotherapy, Immunotherapy and Novel Treatment Options for Different Subtypes of Salivary Gland Cancer
por: Mueller, Sarina K., et al.
Publicado: (2022)

Questionnaire-based detection of immune-related adverse events in cancer patients treated with PD-1/PD-L1 immune checkpoint inhibitors
por: Griewing, Luisa Maria, et al.
Publicado: (2021)

Anti-inflammatory effects of an autologous gold-based serum therapy in osteoarthritis patients
por: Feldt, Jessica, et al.
Publicado: (2022)

Immune biological rationales for the design of combined radio- and immunotherapies
por: Hader, Michael, et al.
Publicado: (2020)

Radon Improves Clinical Response in an Animal Model of Rheumatoid Arthritis Accompanied by Increased Numbers of Peripheral Blood B Cells and Interleukin-5 Concentration
por: Deloch, Lisa, et al.
Publicado: (2022)

The Effect of Hyperthermia and Radiotherapy Sequence on Cancer Cell Death and the Immune Phenotype of Breast Cancer Cells
por: Sengedorj, Azzaya, et al.
Publicado: (2022)

Definitive Radiochemotherapie von lokal fortgeschrittenen Kopf-Hals-Tumoren in Kombination mit Immuncheckpointinhibition – neue Konzepte gefragt
por: Hecht, Markus, et al.
Publicado: (2021)

The Distribution of Pelvic Nodal Metastases in Prostate Cancer Reveals Potential to Advance and Personalize Pelvic Radiotherapy
por: Filimonova, Irina, et al.
Publicado: (2021)

Radiotherapy combined with docetaxel alters the immune phenotype of HNSCC cells and results in increased surface expression of CD137 and release of HMGB1 of specifically HPV-positive tumor cells
por: Grottker, Fridolin, et al.
Publicado: (2023)

Adaptive radiotherapy and the dosimetric impact of inter- and intrafractional motion on the planning target volume for prostate cancer patients
por: Böckelmann, Felix, et al.
Publicado: (2020)

Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines
por: Schatz, Julia, et al.
Publicado: (2022)

Low-Dose Radiotherapy Ameliorates Advanced Arthritis in hTNF-α tg Mice by Particularly Positively Impacting on Bone Metabolism
por: Deloch, Lisa, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_otl8p9t37vb9j6djlagn16l2tn