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A Method to Generate and Rescue Recombinant Adenovirus Devoid of Replication-Competent Particles in Animal-Origin-Free Culture Medium

Adenoviruses are promising vectors for vaccine production and gene therapy. Despite all the efforts in removing animal-derived components such as fetal bovine serum (FBS) during the production of adenovirus vector (AdV), FBS is still frequently employed in the early stages of production. Conventiona...

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Detalles Bibliográficos
Autores principales: Elahi, Seyyed Mehdy, Jiang, Jennifer, Nazemi-Moghaddam, Nazila, Gilbert, Rénald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674172/
https://www.ncbi.nlm.nih.gov/pubmed/38005830
http://dx.doi.org/10.3390/v15112152