Integrase Defective Lentiviral Vector Promoter Impacts Transgene Expression in Target Cells and Magnitude of Vector-Induced Immune Responses

Integrase defective lentiviral vectors (IDLVs) are a promising vaccine delivery platform given their ability to induce high magnitude and durable antigen-specific immune responses. IDLVs based on the simian immunodeficiency virus (SIV) are significantly more efficient at transducing human and simian...

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Detalles Bibliográficos
Autores principales: Mahesh, Sneha, Li, Jenny, Travieso, Tatianna, Psaradelli, Danai, Negri, Donatella, Klotman, Mary, Cara, Andrea, Blasi, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674321/
https://www.ncbi.nlm.nih.gov/pubmed/38005931
http://dx.doi.org/10.3390/v15112255

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