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Endogenous FGF1 Deficiency Aggravates Doxorubicin-Induced Hepatotoxicity

Doxorubicin (DOX) is a broad-spectrum antineoplastic agent that widely used in clinic. However, its application is largely limited by its toxicity in multiple organs. Fibroblast growth factor 1 (FGF1) showed protective potential in various liver diseases, but the role of endogenous FGF1 in DOX-induc...

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Detalles Bibliográficos
Autores principales: Gu, Chunjie, Liu, Zijuan, Li, Yingjian, Yi, Mei, Wang, Simeng, Fan, Xia, Sun, Da, Zhang, Chi, Yan, Xiaoqing, Wu, Guicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674342/
https://www.ncbi.nlm.nih.gov/pubmed/37999577
http://dx.doi.org/10.3390/toxics11110925