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Population Pharmacodynamic Modelling of the CD19+ Suppression Effects of Rituximab in Paediatric Patients with Neurological and Autoimmune Diseases
Background: Limited pharmacotherapy and the failure of conventional treatments in complex pathologies in children lead to increased off-label use of rituximab. We aimed to characterize the time course of CD19+ B lymphocytes (CD19+) under treatment with intravenous rituximab in children with neurolog...
Autores principales: | Riva, Natalia, Brstilo, Lucas, Sancho-Araiz, Aymara, Molina, Manuel, Savransky, Andrea, Roffé, Georgina, Sanz, Marianela, Tenembaum, Silvia, Katsicas, Maria M., Trocóniz, Iñaki F., Schaiquevich, Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674351/ https://www.ncbi.nlm.nih.gov/pubmed/38004515 http://dx.doi.org/10.3390/pharmaceutics15112534 |
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