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Development of a Novel In Vitro Model to Study Lymphatic Uptake of Drugs via Artificial Chylomicrons
The lymphatic system plays a crucial role in the absorption of lipophilic drugs, making it an important route for drug delivery. In this study, an in vitro model using Intralipid(®) was developed to investigate the lymphatic uptake of drugs. The model was validated using cannabidiol, halofantrine, q...
Autores principales: | Yousef, Malaz, Park, Chulhun, Henostroza, Mirla, Bou Chacra, Nadia, Davies, Neal M., Löbenberg, Raimar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674476/ https://www.ncbi.nlm.nih.gov/pubmed/38004512 http://dx.doi.org/10.3390/pharmaceutics15112532 |
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