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A Retrospective Analysis of Porcine Circovirus Type 3 in Samples Collected from 2008 to 2021 in Mexico

Porcine circovirus type 3 (PCV3) is a nonenveloped virus of the Circoviridae family. This virus has been identified in pigs of different ages and pigs with several clinical manifestations of the disease or even in apparently healthy pigs. While PCV3 was first reported in 2015, several retrospective...

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Autores principales: Reséndiz-Sandoval, Mónica, Vázquez-García, Verónica A., Contreras-Vega, Kenneth, Melgoza-González, Edgar A., Mata-Haro, Verónica, Gimenez-Lirola, Luis, Hernández, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674543/
https://www.ncbi.nlm.nih.gov/pubmed/38005901
http://dx.doi.org/10.3390/v15112225
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author Reséndiz-Sandoval, Mónica
Vázquez-García, Verónica A.
Contreras-Vega, Kenneth
Melgoza-González, Edgar A.
Mata-Haro, Verónica
Gimenez-Lirola, Luis
Hernández, Jesús
author_facet Reséndiz-Sandoval, Mónica
Vázquez-García, Verónica A.
Contreras-Vega, Kenneth
Melgoza-González, Edgar A.
Mata-Haro, Verónica
Gimenez-Lirola, Luis
Hernández, Jesús
author_sort Reséndiz-Sandoval, Mónica
collection PubMed
description Porcine circovirus type 3 (PCV3) is a nonenveloped virus of the Circoviridae family. This virus has been identified in pigs of different ages and pigs with several clinical manifestations of the disease or even in apparently healthy pigs. While PCV3 was first reported in 2015, several retrospective studies have reported the virus before that year. The earliest report indicates that PCV3 has been circulated in swine farms since 1996. In this study, we evaluated the presence of PCV3 in samples collected in Mexico in 2008, 2015, 2020, and 2021. This study assessed PCV3 DNA by qPCR and antibodies against CAP protein by indirect ELISA. The results showed that PCV3 (DNA and anti-CAP antibodies) was detected in the samples collected from 2008 to 2021. The highest prevalence was in 2008 (100%), and the lowest was in 2015 (negative). Genetic analysis of ORF2 showed that the virus identified belonged to genotype a, as most of the viruses identified thus far. PCV3 was detected in samples from piglets with respiratory signs and growth retardation, sows with reproductive failure, or asymptomatic piglets and sows. Pigs with respiratory signs, growth retardation, or reproductive failure had a higher prevalence of antibodies and qPCR-positive samples. In conclusion, this study showed that PCV3 has been circulating in Mexico since 2008 and that PCV3 DNA and antibodies were more prevalent in samples from pigs with clinical manifestations of diseases.
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spelling pubmed-106745432023-11-08 A Retrospective Analysis of Porcine Circovirus Type 3 in Samples Collected from 2008 to 2021 in Mexico Reséndiz-Sandoval, Mónica Vázquez-García, Verónica A. Contreras-Vega, Kenneth Melgoza-González, Edgar A. Mata-Haro, Verónica Gimenez-Lirola, Luis Hernández, Jesús Viruses Article Porcine circovirus type 3 (PCV3) is a nonenveloped virus of the Circoviridae family. This virus has been identified in pigs of different ages and pigs with several clinical manifestations of the disease or even in apparently healthy pigs. While PCV3 was first reported in 2015, several retrospective studies have reported the virus before that year. The earliest report indicates that PCV3 has been circulated in swine farms since 1996. In this study, we evaluated the presence of PCV3 in samples collected in Mexico in 2008, 2015, 2020, and 2021. This study assessed PCV3 DNA by qPCR and antibodies against CAP protein by indirect ELISA. The results showed that PCV3 (DNA and anti-CAP antibodies) was detected in the samples collected from 2008 to 2021. The highest prevalence was in 2008 (100%), and the lowest was in 2015 (negative). Genetic analysis of ORF2 showed that the virus identified belonged to genotype a, as most of the viruses identified thus far. PCV3 was detected in samples from piglets with respiratory signs and growth retardation, sows with reproductive failure, or asymptomatic piglets and sows. Pigs with respiratory signs, growth retardation, or reproductive failure had a higher prevalence of antibodies and qPCR-positive samples. In conclusion, this study showed that PCV3 has been circulating in Mexico since 2008 and that PCV3 DNA and antibodies were more prevalent in samples from pigs with clinical manifestations of diseases. MDPI 2023-11-08 /pmc/articles/PMC10674543/ /pubmed/38005901 http://dx.doi.org/10.3390/v15112225 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Reséndiz-Sandoval, Mónica
Vázquez-García, Verónica A.
Contreras-Vega, Kenneth
Melgoza-González, Edgar A.
Mata-Haro, Verónica
Gimenez-Lirola, Luis
Hernández, Jesús
A Retrospective Analysis of Porcine Circovirus Type 3 in Samples Collected from 2008 to 2021 in Mexico
title A Retrospective Analysis of Porcine Circovirus Type 3 in Samples Collected from 2008 to 2021 in Mexico
title_full A Retrospective Analysis of Porcine Circovirus Type 3 in Samples Collected from 2008 to 2021 in Mexico
title_fullStr A Retrospective Analysis of Porcine Circovirus Type 3 in Samples Collected from 2008 to 2021 in Mexico
title_full_unstemmed A Retrospective Analysis of Porcine Circovirus Type 3 in Samples Collected from 2008 to 2021 in Mexico
title_short A Retrospective Analysis of Porcine Circovirus Type 3 in Samples Collected from 2008 to 2021 in Mexico
title_sort retrospective analysis of porcine circovirus type 3 in samples collected from 2008 to 2021 in mexico
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674543/
https://www.ncbi.nlm.nih.gov/pubmed/38005901
http://dx.doi.org/10.3390/v15112225
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