Cargando…

An Infant with Measles Developed Ecthyma Gangrenosum Caused by Coagulase-Negative Staphylococcus: A Rare Case Report from Somalia

INTRODUCTION AND IMPORTANCE: Ecthyma gangrenosum is a skin lesion that can be caused by either bacterial hematogenous seeding or a primary skin infection. Despite being the most frequent causal agent, Pseudomonas aeruginosa is not the only bacteria that has been involved. Other types of bacteria may...

Descripción completa

Detalles Bibliográficos
Autores principales: Ali, Ahmed Isse, Mohamed, Abdullahi Ali, Hirsi, Ibrahim Mohamed, Ali, Mohamed Nur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674559/
https://www.ncbi.nlm.nih.gov/pubmed/38020580
http://dx.doi.org/10.2147/IMCRJ.S432275
_version_ 1785149721945309184
author Ali, Ahmed Isse
Mohamed, Abdullahi Ali
Hirsi, Ibrahim Mohamed
Ali, Mohamed Nur
author_facet Ali, Ahmed Isse
Mohamed, Abdullahi Ali
Hirsi, Ibrahim Mohamed
Ali, Mohamed Nur
author_sort Ali, Ahmed Isse
collection PubMed
description INTRODUCTION AND IMPORTANCE: Ecthyma gangrenosum is a skin lesion that can be caused by either bacterial hematogenous seeding or a primary skin infection. Despite being the most frequent causal agent, Pseudomonas aeruginosa is not the only bacteria that has been involved. Other types of bacteria may also be implicated in the etiology of EG: cocci bacteria, both gram-positive and gram-negative. CASE PRESENTATION: Here, we report the case of a 10-month-old male infant who developed ecthyma gangrenosum after a measles infection. At the time of admission, the patient had a high fever of about 40.3°C and appeared conscious. Physical examination revealed several skin lesions that were in various stages of development and appeared as nodules with a central crust and round, ulcerated, necrotic papules in the face, chest, and upper extremities. Laboratory tests showed CRP of 25 mg/l, LDH of 579 U/L, WBC of 15.06 × 1000/mm3, and absolute neutrophils of 1930/mm3 (12.8%). The result of the culture showed coagulase-negative Staphylococcus. According to the drug susceptibility test results, intravenous Vancomycin (20 mg/kg per dose, 3 times daily) should be started. A coagulase-negative Staphylococcus was eliminated as a result of this defervescence. The necrotic lesion was surgically removed from the patient. CLINICAL DISCUSSION: Ecthyma gangrenosum is the all-over-the-body cutaneous manifestation of pseudomonas infection in sepsis patients. Patients who suffer from severe illnesses. Immune deficiencies commonly increase the chance of acquiring EG. Our patient had a history of measles, which led to neutropenia before developing EG. The management of ecthyma gangrenosum requires early identification and antimicrobial treatment. CONCLUSION: We describe a measles patient who developed coagulase-negative Staphylococcus ecthyma gangrenosum and had good results from both surgical debridement and systemic antibiotics. Our case serves as an example of the uncommon presentation of ecthyma gangrenosum. This example emphasizes the value of an early diagnosis and vigorous antimicrobial therapy in cases where ecthyma gangrenosum is clinically suspected.
format Online
Article
Text
id pubmed-10674559
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-106745592023-11-20 An Infant with Measles Developed Ecthyma Gangrenosum Caused by Coagulase-Negative Staphylococcus: A Rare Case Report from Somalia Ali, Ahmed Isse Mohamed, Abdullahi Ali Hirsi, Ibrahim Mohamed Ali, Mohamed Nur Int Med Case Rep J Case Report INTRODUCTION AND IMPORTANCE: Ecthyma gangrenosum is a skin lesion that can be caused by either bacterial hematogenous seeding or a primary skin infection. Despite being the most frequent causal agent, Pseudomonas aeruginosa is not the only bacteria that has been involved. Other types of bacteria may also be implicated in the etiology of EG: cocci bacteria, both gram-positive and gram-negative. CASE PRESENTATION: Here, we report the case of a 10-month-old male infant who developed ecthyma gangrenosum after a measles infection. At the time of admission, the patient had a high fever of about 40.3°C and appeared conscious. Physical examination revealed several skin lesions that were in various stages of development and appeared as nodules with a central crust and round, ulcerated, necrotic papules in the face, chest, and upper extremities. Laboratory tests showed CRP of 25 mg/l, LDH of 579 U/L, WBC of 15.06 × 1000/mm3, and absolute neutrophils of 1930/mm3 (12.8%). The result of the culture showed coagulase-negative Staphylococcus. According to the drug susceptibility test results, intravenous Vancomycin (20 mg/kg per dose, 3 times daily) should be started. A coagulase-negative Staphylococcus was eliminated as a result of this defervescence. The necrotic lesion was surgically removed from the patient. CLINICAL DISCUSSION: Ecthyma gangrenosum is the all-over-the-body cutaneous manifestation of pseudomonas infection in sepsis patients. Patients who suffer from severe illnesses. Immune deficiencies commonly increase the chance of acquiring EG. Our patient had a history of measles, which led to neutropenia before developing EG. The management of ecthyma gangrenosum requires early identification and antimicrobial treatment. CONCLUSION: We describe a measles patient who developed coagulase-negative Staphylococcus ecthyma gangrenosum and had good results from both surgical debridement and systemic antibiotics. Our case serves as an example of the uncommon presentation of ecthyma gangrenosum. This example emphasizes the value of an early diagnosis and vigorous antimicrobial therapy in cases where ecthyma gangrenosum is clinically suspected. Dove 2023-11-20 /pmc/articles/PMC10674559/ /pubmed/38020580 http://dx.doi.org/10.2147/IMCRJ.S432275 Text en © 2023 Ali et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Ali, Ahmed Isse
Mohamed, Abdullahi Ali
Hirsi, Ibrahim Mohamed
Ali, Mohamed Nur
An Infant with Measles Developed Ecthyma Gangrenosum Caused by Coagulase-Negative Staphylococcus: A Rare Case Report from Somalia
title An Infant with Measles Developed Ecthyma Gangrenosum Caused by Coagulase-Negative Staphylococcus: A Rare Case Report from Somalia
title_full An Infant with Measles Developed Ecthyma Gangrenosum Caused by Coagulase-Negative Staphylococcus: A Rare Case Report from Somalia
title_fullStr An Infant with Measles Developed Ecthyma Gangrenosum Caused by Coagulase-Negative Staphylococcus: A Rare Case Report from Somalia
title_full_unstemmed An Infant with Measles Developed Ecthyma Gangrenosum Caused by Coagulase-Negative Staphylococcus: A Rare Case Report from Somalia
title_short An Infant with Measles Developed Ecthyma Gangrenosum Caused by Coagulase-Negative Staphylococcus: A Rare Case Report from Somalia
title_sort infant with measles developed ecthyma gangrenosum caused by coagulase-negative staphylococcus: a rare case report from somalia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674559/
https://www.ncbi.nlm.nih.gov/pubmed/38020580
http://dx.doi.org/10.2147/IMCRJ.S432275
work_keys_str_mv AT aliahmedisse aninfantwithmeaslesdevelopedecthymagangrenosumcausedbycoagulasenegativestaphylococcusararecasereportfromsomalia
AT mohamedabdullahiali aninfantwithmeaslesdevelopedecthymagangrenosumcausedbycoagulasenegativestaphylococcusararecasereportfromsomalia
AT hirsiibrahimmohamed aninfantwithmeaslesdevelopedecthymagangrenosumcausedbycoagulasenegativestaphylococcusararecasereportfromsomalia
AT alimohamednur aninfantwithmeaslesdevelopedecthymagangrenosumcausedbycoagulasenegativestaphylococcusararecasereportfromsomalia
AT aliahmedisse infantwithmeaslesdevelopedecthymagangrenosumcausedbycoagulasenegativestaphylococcusararecasereportfromsomalia
AT mohamedabdullahiali infantwithmeaslesdevelopedecthymagangrenosumcausedbycoagulasenegativestaphylococcusararecasereportfromsomalia
AT hirsiibrahimmohamed infantwithmeaslesdevelopedecthymagangrenosumcausedbycoagulasenegativestaphylococcusararecasereportfromsomalia
AT alimohamednur infantwithmeaslesdevelopedecthymagangrenosumcausedbycoagulasenegativestaphylococcusararecasereportfromsomalia