Discovery and Characterization of a Dual-Function Peptide Derived from Bitter Gourd Seed Protein Using Two Orthogonal Bioassay-Guided Fractionations Coupled with In Silico Analysis

The hydrolysate of bitter gourd seed protein, digested by the combined gastrointestinal proteases (BGSP-GPs), exhibited the most potent inhibition on angiotensin-I-converting enzyme (ACE) with an IC(50) value of 48.1 ± 2.0 µg/mL. Using two independent bioassay-guided fractionations, fraction F5 from...

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Detalles Bibliográficos
Autores principales: Hung, Wei-Ting, Sutopo, Christoper Caesar Yudho, Wu, Mei-Li, Hsu, Jue-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674851/
https://www.ncbi.nlm.nih.gov/pubmed/38004494
http://dx.doi.org/10.3390/ph16111629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674851/
https://www.ncbi.nlm.nih.gov/pubmed/38004494
http://dx.doi.org/10.3390/ph16111629

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