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Identification of 2,4-Diaminoquinazoline Derivative as a Potential Small-Molecule Inhibitor against Chikungunya and Ross River Viruses

Alphaviruses are serious zoonotic threats responsible for significant morbidity, causing arthritis or encephalitis. So far, no licensed drugs or vaccines are available to combat alphaviral infections. About 300,000 chikungunya virus (CHIKV) infections have been reported in 2023, with more than 300 d...

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Detalles Bibliográficos
Autores principales: Saha, Amrita, Acharya, Badri Narayan, Parida, Manmohan, Saxena, Nandita, Rajaiya, Jaya, Dash, Paban Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674894/
https://www.ncbi.nlm.nih.gov/pubmed/38005871
http://dx.doi.org/10.3390/v15112194