Vaccination with an HIV T-Cell Immunogen (HTI) Using DNA Primes Followed by a ChAdOx1-MVA Boost Is Immunogenic in Gut Microbiota-Depleted Mice despite Low IL-22 Serum Levels

Despite the important role of gut microbiota in the maturation of the immune system, little is known about its impact on the development of T-cell responses to vaccination. Here, we immunized C57BL/6 mice with a prime-boost regimen using DNA plasmid, the Chimpanzee Adenovirus, and the modified Vacci...

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Detalles Bibliográficos
Autores principales: Elizalde-Torrent, Aleix, Borgognone, Alessandra, Casadellà, Maria, Romero-Martin, Luis, Escribà, Tuixent, Parera, Mariona, Rosales-Salgado, Yaiza, Díaz-Pedroza, Jorge, Català-Moll, Francesc, Noguera-Julian, Marc, Brander, Christian, Paredes, Roger, Olvera, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675013/
https://www.ncbi.nlm.nih.gov/pubmed/38005995
http://dx.doi.org/10.3390/vaccines11111663

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