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Tailoring Risperidone-Loaded Glycethosomal In Situ Gels Using Box–Behnken Design for Treatment of Schizophrenia-Induced Rats via Intranasal Route
Schizophrenic patients often face challenges with adherence to oral regimens. The study aimed to highlight the potentiality of intranasal ethanol/glycerin-containing lipid-nanovesicles (glycethosomes) incorporated into in situ gels for sustaining anti-psychotic risperidone (RS) release. The Box–Behn...
Autores principales: | Abdallah, Marwa H., El-Horany, Hemat El-Sayed, El-Nahas, Hanan M., Ibrahim, Tarek M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675145/ https://www.ncbi.nlm.nih.gov/pubmed/38004501 http://dx.doi.org/10.3390/pharmaceutics15112521 |
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