The Application of Mesenchymal Stem Cells in Future Vaccine Synthesis

Vaccines have significant potential in treating and/or preventing diseases, yet there remain challenges in developing effective vaccines against some diseases, such as AIDS and certain tumors. Mesenchymal stem cells (MSCs), a subset of cells with low immunogenicity, high proliferation potential, and...

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Autores principales: Zhang, Rui, Duan, Xingxiang, Liu, Ye, Xu, Jia, Al-bashari, Abdullkhaleg Ali Ghaleb, Ye, Peng, Ye, Qingsong, He, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675160/
https://www.ncbi.nlm.nih.gov/pubmed/38005963
http://dx.doi.org/10.3390/vaccines11111631
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author Zhang, Rui
Duan, Xingxiang
Liu, Ye
Xu, Jia
Al-bashari, Abdullkhaleg Ali Ghaleb
Ye, Peng
Ye, Qingsong
He, Yan
author_facet Zhang, Rui
Duan, Xingxiang
Liu, Ye
Xu, Jia
Al-bashari, Abdullkhaleg Ali Ghaleb
Ye, Peng
Ye, Qingsong
He, Yan
author_sort Zhang, Rui
collection PubMed
description Vaccines have significant potential in treating and/or preventing diseases, yet there remain challenges in developing effective vaccines against some diseases, such as AIDS and certain tumors. Mesenchymal stem cells (MSCs), a subset of cells with low immunogenicity, high proliferation potential, and an abundant source of extracellular vesicles (EVs), represent one of the novel and promising vaccine platforms. This review describes the unique features and potential mechanisms of MSCs as a novel vaccine platform. We also cover aspects such as the safety and stability of MSCs that warrant future in-depth studies.
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spelling pubmed-106751602023-10-24 The Application of Mesenchymal Stem Cells in Future Vaccine Synthesis Zhang, Rui Duan, Xingxiang Liu, Ye Xu, Jia Al-bashari, Abdullkhaleg Ali Ghaleb Ye, Peng Ye, Qingsong He, Yan Vaccines (Basel) Review Vaccines have significant potential in treating and/or preventing diseases, yet there remain challenges in developing effective vaccines against some diseases, such as AIDS and certain tumors. Mesenchymal stem cells (MSCs), a subset of cells with low immunogenicity, high proliferation potential, and an abundant source of extracellular vesicles (EVs), represent one of the novel and promising vaccine platforms. This review describes the unique features and potential mechanisms of MSCs as a novel vaccine platform. We also cover aspects such as the safety and stability of MSCs that warrant future in-depth studies. MDPI 2023-10-24 /pmc/articles/PMC10675160/ /pubmed/38005963 http://dx.doi.org/10.3390/vaccines11111631 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Rui
Duan, Xingxiang
Liu, Ye
Xu, Jia
Al-bashari, Abdullkhaleg Ali Ghaleb
Ye, Peng
Ye, Qingsong
He, Yan
The Application of Mesenchymal Stem Cells in Future Vaccine Synthesis
title The Application of Mesenchymal Stem Cells in Future Vaccine Synthesis
title_full The Application of Mesenchymal Stem Cells in Future Vaccine Synthesis
title_fullStr The Application of Mesenchymal Stem Cells in Future Vaccine Synthesis
title_full_unstemmed The Application of Mesenchymal Stem Cells in Future Vaccine Synthesis
title_short The Application of Mesenchymal Stem Cells in Future Vaccine Synthesis
title_sort application of mesenchymal stem cells in future vaccine synthesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675160/
https://www.ncbi.nlm.nih.gov/pubmed/38005963
http://dx.doi.org/10.3390/vaccines11111631
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