Cargando…

Independent Protection and Influence of the Spike-Specific Antibody Response of SARS-CoV-2 Nucleocapsid Protein (N) in Whole-Virion Vaccines

Of all of the components in SARS-CoV-2 inactivated vaccines, nucleocapsid protein (N) is the most abundant and highly conserved protein. However, the function of N in these vaccines, especially its influence on the targeted spike protein’s response, remains unknown. In this study, the immunization o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Huijie, Xie, Ying, Lu, Shuaiyao, Sun, Yufang, Wang, Kaiqin, Li, Shuyan, Wang, Junzhi, Liao, Guoyang, Li, Changgui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675215/ https://www.ncbi.nlm.nih.gov/pubmed/38006013 http://dx.doi.org/10.3390/vaccines11111681

Ejemplares similares

Antibody detection of SARS-CoV spike and nucleocapsid protein
por: Chang, Mau-Sun, et al.
Publicado: (2004)

Spike-based COVID-19 immunization increases antibodies to nucleocapsid antigen
por: Dobaño, Carlota, et al.
Publicado: (2022)

Preclinical immunogenicity assessment of a cell-based inactivated whole-virion H5N1 influenza vaccine
por: Zhang, Zhegang, et al.
Publicado: (2022)

Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions
por: Ujike, Makoto, et al.
Publicado: (2015)

The Quantification of Spike Proteins in the Inactivated SARS-CoV-2 Vaccines of the Prototype, Delta, and Omicron Variants by LC–MS
por: Xu, Kangwei, et al.
Publicado: (2023)

Detection of SARS-CoV-2 Nucleocapsid, Spike, and Neutralizing Antibodies in Vaccinated Japanese
por: Midorikawa, Rie, et al.
Publicado: (2022)

Antibody-Mediated Immobilization of Virions in Mucus
por: Jensen, Melanie A., et al.
Publicado: (2019)

Modulation of the HIV nucleocapsid dynamics finely tunes its RNA-binding properties during virion genesis
por: Mouhand, Assia, et al.
Publicado: (2018)

High-resolution structural analysis of enterovirus-reactive polyclonal antibodies in complex with whole virions
por: Antanasijevic, Aleksandar, et al.
Publicado: (2022)

Serum Level of Anti-Nucleocapsid, but Not Anti-Spike Antibody, Is Associated with Improvement of Long COVID Symptoms
por: Varnai, Reka, et al.
Publicado: (2022)

Protection from COVID-19 with a VSV-based vaccine expressing the spike and nucleocapsid proteins
por: O’Donnell, Kyle L., et al.
Publicado: (2022)

Tracking hantavirus nucleocapsid protein using intracellular antibodies
por: Li, Jiandong, et al.
Publicado: (2010)

Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors
por: Sahin, Mehmet, et al.
Publicado: (2022)

Thiopurines inhibit coronavirus Spike protein processing and incorporation into progeny virions
por: Pringle, Eric S., et al.
Publicado: (2022)

Anti-spike, Anti-nucleocapsid and Neutralizing Antibodies in SARS-CoV-2 Inpatients and Asymptomatic Individuals
por: Brochot, Etienne, et al.
Publicado: (2020)

Evaluation of Nucleocapsid and Spike Protein-Based Enzyme-Linked Immunosorbent Assays for Detecting Antibodies against SARS-CoV-2
por: Liu, Wanbing, et al.
Publicado: (2020)

Development of an antibody-dependent cellular cytotoxicity reporter assay for measuring anti-Middle East Respiratory Syndrome antibody bioactivity
por: Cao, Junxia, et al.
Publicado: (2020)

A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions
por: Vercruysse, Thomas, et al.
Publicado: (2012)

Detection of Nucleocapsid Antibody to SARS-CoV-2 is More Sensitive than Antibody to Spike Protein in COVID-19 Patients
por: Burbelo, Peter D., et al.
Publicado: (2020)

Spike Protein Antibodies Mediate the Apparent Correlation between SARS-CoV-2 Nucleocapsid Antibodies and Neutralization Test Results
por: Perkmann, Thomas, et al.
Publicado: (2021)

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity
por: Zhang, Lizhou, et al.
Publicado: (2020)

Evaluation of antibody responses against the whole virions of goatpox and sheeppox viruses after subcutaneous immunization of rabbits
por: Hurisa, Takele Tesgera, et al.
Publicado: (2022)

Detection of breastmilk antibodies targeting SARS-CoV-2 nucleocapsid, spike and receptor-binding-domain antigens
por: Favara, D. M., et al.
Publicado: (2020)

IgG Antibodies Develop to Spike but Not to the Nucleocapsid Viral Protein in Many Asymptomatic and Light COVID-19 Cases
por: Tutukina, Maria, et al.
Publicado: (2021)

Kinetics of Nucleocapsid, Spike and Neutralizing Antibodies, and Viral Load in Patients with Severe COVID-19 Treated with Convalescent Plasma
por: Thomopoulos, Thomas P., et al.
Publicado: (2021)

Detection of Anti-SARS-CoV-2 Nucleocapsid and Spike Antibodies in Patients with Coronavirus Disease 2019 in Japan
por: Furukawa, Hiroshi, et al.
Publicado: (2022)

IgG antibody response against nucleocapsid and spike protein post-SARS-CoV-2 infection
por: Choudhary, Hari Ram, et al.
Publicado: (2021)

Comparison of nucleocapsid and spike antibody ELISAs for determining SARS‐CoV‐2 seropositivity in Kenyan women and infants
por: Fish, Carolyn S., et al.
Publicado: (2022)

A novel colorimetric biosensor for detecting SARS-CoV-2 by utilizing the interaction between nucleocapsid antibody and spike proteins
por: Bhattacharjee, Abhishek, et al.
Publicado: (2022)

Antibodies to Nucleocapsid Are Not Diagnostic for Long COVID
por: Brandt, C. T., et al.
Publicado: (2023)

Immunomolecular assay based on selective virion capture by spike antibody and viral nucleic acid amplification for detecting intact SARS-CoV-2 particles
por: Wu, Xiaoli, et al.
Publicado: (2022)

IgG and IgM antibody formation to spike and nucleocapsid proteins in COVID-19 characterized by multiplex immunoblot assays
por: Shah, Jyotsna, et al.
Publicado: (2021)

Mild SARS-CoV-2 Illness Is Not Associated with Reinfections and Provides Persistent Spike, Nucleocapsid, and Virus-Neutralizing Antibodies
por: Schuler, Charles F., et al.
Publicado: (2021)

Antibody Response to the SARS-CoV-2 Spike and Nucleocapsid Proteins in Patients with Different COVID-19 Clinical Profiles
por: Soares, Sinei Ramos, et al.
Publicado: (2023)

Characterization of a recombinant coronavirus infectious bronchitis virus with distinct S1 subunits of spike and nucleocapsid genes and a 3′ untranslated region
por: Liu, Xiaoli, et al.
Publicado: (2013)

Why HIV Virions Have Low Numbers of Envelope Spikes: Implications for Vaccine Development
por: Schiller, John, et al.
Publicado: (2014)

Structure of the Ebola virus glycoprotein spike within the virion envelope at 11 Å resolution
por: Beniac, Daniel R., et al.
Publicado: (2017)

Topography, Spike Dynamics, and Nanomechanics of Individual Native SARS-CoV-2 Virions
por: Kiss, Bálint, et al.
Publicado: (2021)

Topography, Spike Dynamics and Nanomechanics of Individual Native SARS-CoV-2 Virions
por: Kiss, Balint, et al.
Publicado: (2021)

SARS COV-2 anti-nucleocapsid and anti-spike antibodies in an emergency department healthcare worker cohort: September 2020 – April 2021
por: Wang, Ralph C., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7cs9tr4oi1orqckgqk8ucd7c47