Cargando…

Evaluation of a Three-Fluid Nozzle Spraying Process for Facilitating Spray Drying of Hydrophilic Polymers for the Creation of Amorphous Solid Dispersions

Amorphous solid dispersions (ASDs) enable formulations to improve the solubility of poorly soluble active pharmaceutical ingredients (APIs). The amorphous state is reached through the disruption of the crystalline lattice of an API resulting in an increased apparent solubility with faster disintegra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mueller, Lena Karin, Halstenberg, Laura, Di Gallo, Nicole, Kipping, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675266/ https://www.ncbi.nlm.nih.gov/pubmed/38004521 http://dx.doi.org/10.3390/pharmaceutics15112542

Ejemplares similares

Effect of Storage Humidity on Physical Stability of Spray-Dried Naproxen Amorphous Solid Dispersions with Polyvinylpyrrolidone: Two Fluid Nozzle vs. Three Fluid Nozzle
por: Bhujbal, Sonal V., et al.
Publicado: (2021)

Water-Induced Phase Separation of Spray-Dried Amorphous Solid Dispersions
por: Li, Na, et al.
Publicado: (2020)

Predicting process design spaces for spray drying amorphous solid dispersions
por: Dohrn, Stefanie, et al.
Publicado: (2021)

Amorphous Solid Dispersions Layered onto Pellets—An Alternative to Spray Drying?
por: Neuwirth, Marius, et al.
Publicado: (2023)

Spray-Dried Paracetamol/Polyvinylpyrrolidone Amorphous Solid Dispersions: Part I—Stability of Powders and Tablets
por: Ritters, Lena, et al.
Publicado: (2021)

Spray-Dried Amorphous Solid Dispersions of Atorvastatin Calcium for Improved Supersaturation and Oral Bioavailability
por: Kwon, Jaewook, et al.
Publicado: (2019)

Superiority of Mesoporous Silica-Based Amorphous Formulations over Spray-Dried Solid Dispersions
por: Zhang, Hongwei, et al.
Publicado: (2022)

Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying
por: Schönfeld, Barbara V., et al.
Publicado: (2021)

The Value of Bead Coating in the Manufacturing of Amorphous Solid Dispersions: A Comparative Evaluation with Spray Drying
por: Boel, Eline, et al.
Publicado: (2022)

Evaluation of Pharmacobezoar Formation from Suspensions of Spray-Dried Amorphous Solid Dispersions: An MRI Study in Rats
por: Gierke, Hannes, et al.
Publicado: (2023)

Comparison of Amorphous Solid Dispersions of Spironolactone Prepared by Spray Drying and Electrospinning: The Influence of the Preparation Method on the Dissolution Properties
por: Szabó, Edina, et al.
Publicado: (2020)

Prediction of the Impact of Nozzle Geometry on Spray Characteristics
por: Mohamed, Mahmoud Abd El-Aziz, et al.
Publicado: (2021)

Developing pH-Modulated Spray Dried Amorphous Solid Dispersion of Candesartan Cilexetil with Enhanced In Vitro and In Vivo Performance
por: Poudel, Surendra, et al.
Publicado: (2021)

Development of spray-dried amorphous solid dispersions of tadalafil using glycyrrhizin for enhanced dissolution and aphrodisiac activity in male rats
por: Muqtader Ahmed, Mohammed, et al.
Publicado: (2020)

Asymmetric Spray Characteristics According to Y-Jet Nozzle Orifice Shape and Spray Conditions
por: Lee, Sang Ji, et al.
Publicado: (2023)

Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying
por: Craye, Goedele, et al.
Publicado: (2015)

A Comparison of Microfluidic-Jet Spray Drying, Two-Fluid Nozzle Spray Drying, and Freeze-Drying for Co-Encapsulating β-Carotene, Lutein, Zeaxanthin, and Fish Oil
por: Zhu, Yongchao, et al.
Publicado: (2021)

A novel architecture for achieving high drug loading in amorphous spray dried dispersion tablets
por: Mudie, Deanna M., et al.
Publicado: (2020)

Spray-Dried Amorphous Solid Dispersions of Griseofulvin in HPC/Soluplus/SDS: Elucidating the Multifaceted Impact of SDS as a Minor Component
por: Rahman, Mahbubur, et al.
Publicado: (2020)

Physical Stability and Dissolution of Lumefantrine Amorphous Solid Dispersions Produced by Spray Anti-Solvent Precipitation
por: Bhujbal, Sonal V., et al.
Publicado: (2021)

Amorphicity and Aerosolization of Soluplus-Based Inhalable Spray Dried Powders
por: Adhikari, Bishal Raj, et al.
Publicado: (2022)

Preparation and Characterization of Spray-Dried Hybrid Nanocrystal–Amorphous Solid Dispersions (HyNASDs) for Supersaturation Enhancement of a Slowly Crystallizing Drug
por: Rahman, Mahbubur, et al.
Publicado: (2023)

The effect of adjuvants on spray droplet size from hydraulic nozzles
por: Sijs, Rick, et al.
Publicado: (2020)

Solvent-Assisted Secondary Drying of Spray-Dried Polymers
por: Shepard, Kimberly B., et al.
Publicado: (2020)

Effects of sprayer speed, spray distance, and nozzle arrangement angle on low-flow air-assisted spray deposition
por: Dai, Shiqun, et al.
Publicado: (2023)

HPMCAS-Based Amorphous Solid Dispersions in Clinic: A Review on Manufacturing Techniques (Hot Melt Extrusion and Spray Drying), Marketed Products and Patents
por: Corrie, Leander, et al.
Publicado: (2023)

Revealing facts behind spray dried solid dispersion technology used for solubility enhancement
por: Patel, Bhavesh B., et al.
Publicado: (2015)

Solid Dispersions of Gefitinib Prepared by Spray Drying with Improved Mucoadhesive and Drug Dissolution Properties
por: Mustafa, Wesam W., et al.
Publicado: (2022)

Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
por: Mishra, Jaya, et al.
Publicado: (2018)

A Novel Machine Vision System for the Inspection of Micro-Spray Nozzle
por: Huang, Kuo-Yi, et al.
Publicado: (2015)

Numerical Simulation and Experimental Study for the Impact of In-Flow Nozzle on Spray Characteristics
por: Mohamed, Mahmoud Abd El-Aziz, et al.
Publicado: (2021)

Characterization of Amorphous Solid Dispersion of Pharmaceutical Compound with pH-Dependent Solubility Prepared by Continuous-Spray Granulator
por: Tanaka, Ryoma, et al.
Publicado: (2019)

Development of olanzapine solid dispersion by spray drying technique using screening design for solubility enhancement
por: Patil, Leena, et al.
Publicado: (2023)

Measuring Spray Droplet Size from Agricultural Nozzles Using Laser Diffraction
por: Fritz, Bradley K., et al.
Publicado: (2016)

Investigation of Needle Motion Profile Effect on Diesel Spray in Near-Nozzle Field
por: Gao, Ya, et al.
Publicado: (2022)

Processing of Lipid Nanodispersions into Solid Powders by Spray Drying
por: Steiner, Denise, et al.
Publicado: (2022)

Spray drying handbook
por: Masters, Keith
Publicado: (1988)

Improved Bioavailability and High Photostability of Methotrexate by Spray-Dried Surface-Attached Solid Dispersion with an Aqueous Medium
por: Giri, Bhupendra Raj, et al.
Publicado: (2021)

The Use of a Three-Fluid Atomising Nozzle in the Production of Spray-Dried Theophylline/Salbutamol Sulphate Powders Intended for Pulmonary Delivery
por: Focaroli, Stefano, et al.
Publicado: (2020)

Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
por: Kasten, Georgia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lr8at290v61gfgjl2asr79u6oe