A Non-Nucleotide STING Agonist MSA-2 Synergized with Manganese in Enhancing STING Activation to Elicit Potent Anti-RNA Virus Activity in the Cells

Both Manganese (Mn(2+)) and MSA-2 can activate the downstream signal pathway through stimulator of interferon genes (STING) and induce the expression of type I interferon, which is important for hosts to protect against DNA viruses. However, its effect on RNA viruses remains unknown. In this study,...

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Detalles Bibliográficos
Autores principales: Lin, Hanrui, Zhang, Rui, Xiang, Hanyi, Lin, Xinqian, Huang, Xiongting, Chen, Jingsong, Zhou, Long, Zhang, Zhidong, Li, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675287/
https://www.ncbi.nlm.nih.gov/pubmed/38005816
http://dx.doi.org/10.3390/v15112138

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