The Bacteriophages Therapy of Interdigital Pyoderma Complicated by Cellulitis with Antibiotic-Resistant Pseudomonas aeruginosa in a Dog—Case Report

SIMPLE SUMMARY: In the context of increasingly serious bacterial infections that occur in animals, for which antibiotics no longer respond to therapy, the search of new alternatives is often of vital/major importance for saving patients. A polyvalent suspension of bacteriophages was chosen in this study as an alternative method to combat a skin infection in a dog that was shown to be refractory to antibiotics. Bacteriophage therapy showed significant results, proving their effectiveness in local treatment, as well as in preventing the systemic spread of infection with Pseudomonas aeruginosa in dogs. ABSTRACT: Pseudomonas aeruginosa is a highly pathogenic bacterium with high pathogenicity, that can cause serious infections in all species and especially in dogs. Treatment of the infection induced by this bacterium can be a challenge considering that some strains have developed resistance to most classes of antimicrobials. The use of bacteriophages to alleviate infections caused by Pseudomonas aeruginosa has demonstrated their potential for both internal and external applications. This study aimed to illustrate the treatment with bacteriophages in bacterially complicated skin lesions that do not respond to antimicrobial therapy.