Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature

A simple and highly effective methodology for the cross-coupling of heteroaryl iodides with NN–AuPPh(3) at room temperature is reported. The protocol is based on a novel catalytic system consisting of Pd(2)(dba)(3)·CHCl(3) and the phosphine ligand (Me)CgPPh having an adamantane-like framework. The p...

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Detalles Bibliográficos
Autores principales: Zayakin, Igor, Romanenko, Galina, Bagryanskaya, Irina, Ugrak, Bogdan, Fedin, Matvey, Tretyakov, Evgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675334/
https://www.ncbi.nlm.nih.gov/pubmed/38005383
http://dx.doi.org/10.3390/molecules28227661
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author Zayakin, Igor
Romanenko, Galina
Bagryanskaya, Irina
Ugrak, Bogdan
Fedin, Matvey
Tretyakov, Evgeny
author_facet Zayakin, Igor
Romanenko, Galina
Bagryanskaya, Irina
Ugrak, Bogdan
Fedin, Matvey
Tretyakov, Evgeny
author_sort Zayakin, Igor
collection PubMed
description A simple and highly effective methodology for the cross-coupling of heteroaryl iodides with NN–AuPPh(3) at room temperature is reported. The protocol is based on a novel catalytic system consisting of Pd(2)(dba)(3)·CHCl(3) and the phosphine ligand (Me)CgPPh having an adamantane-like framework. The present protocol was found to be well compatible with various heteroaryl iodides, thus opening new horizons in directed synthesis of functionalized nitronyl nitroxides and high-spin molecules.
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spelling pubmed-106753342023-11-19 Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature Zayakin, Igor Romanenko, Galina Bagryanskaya, Irina Ugrak, Bogdan Fedin, Matvey Tretyakov, Evgeny Molecules Article A simple and highly effective methodology for the cross-coupling of heteroaryl iodides with NN–AuPPh(3) at room temperature is reported. The protocol is based on a novel catalytic system consisting of Pd(2)(dba)(3)·CHCl(3) and the phosphine ligand (Me)CgPPh having an adamantane-like framework. The present protocol was found to be well compatible with various heteroaryl iodides, thus opening new horizons in directed synthesis of functionalized nitronyl nitroxides and high-spin molecules. MDPI 2023-11-19 /pmc/articles/PMC10675334/ /pubmed/38005383 http://dx.doi.org/10.3390/molecules28227661 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zayakin, Igor
Romanenko, Galina
Bagryanskaya, Irina
Ugrak, Bogdan
Fedin, Matvey
Tretyakov, Evgeny
Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature
title Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature
title_full Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature
title_fullStr Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature
title_full_unstemmed Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature
title_short Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature
title_sort catalytic system for cross-coupling of heteroaryl iodides with a nitronyl nitroxide gold derivative at room temperature
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675334/
https://www.ncbi.nlm.nih.gov/pubmed/38005383
http://dx.doi.org/10.3390/molecules28227661
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