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Circularized Nanodiscs for Multivalent Mosaic Display of SARS-CoV-2 Spike Protein Antigens

The emergence of vaccine-evading SARS-CoV-2 variants urges the need for vaccines that elicit broadly neutralizing antibodies (bnAbs). Here, we assess covalently circularized nanodiscs decorated with recombinant SARS-CoV-2 spike glycoproteins from several variants for eliciting bnAbs with vaccination...

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Detalles Bibliográficos
Autores principales: Mabrouk, Moustafa T., Zidan, Asmaa A., Aly, Nihal, Mohammed, Mostafa T., Ghantous, Fadi, Seaman, Michael S., Lovell, Jonathan F., Nasr, Mahmoud L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675430/
https://www.ncbi.nlm.nih.gov/pubmed/38005987
http://dx.doi.org/10.3390/vaccines11111655

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