Scandium Radioisotopes—Toward New Targets and Imaging Modalities

The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic...

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Detalles Bibliográficos
Autores principales: Kilian, Krzysztof, Pyrzyńska, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675654/
https://www.ncbi.nlm.nih.gov/pubmed/38005390
http://dx.doi.org/10.3390/molecules28227668
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author Kilian, Krzysztof
Pyrzyńska, Krystyna
author_facet Kilian, Krzysztof
Pyrzyńska, Krystyna
author_sort Kilian, Krzysztof
collection PubMed
description The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic markers, while radioisotope scandium-47 can be used in the same configuration for targeted therapy. This work presents the latest achievements in the production and processing of radioisotopes and briefly characterizes solutions aimed at increasing the availability of these radioisotopes for research and clinical practice.
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spelling pubmed-106756542023-11-19 Scandium Radioisotopes—Toward New Targets and Imaging Modalities Kilian, Krzysztof Pyrzyńska, Krystyna Molecules Review The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic markers, while radioisotope scandium-47 can be used in the same configuration for targeted therapy. This work presents the latest achievements in the production and processing of radioisotopes and briefly characterizes solutions aimed at increasing the availability of these radioisotopes for research and clinical practice. MDPI 2023-11-19 /pmc/articles/PMC10675654/ /pubmed/38005390 http://dx.doi.org/10.3390/molecules28227668 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kilian, Krzysztof
Pyrzyńska, Krystyna
Scandium Radioisotopes—Toward New Targets and Imaging Modalities
title Scandium Radioisotopes—Toward New Targets and Imaging Modalities
title_full Scandium Radioisotopes—Toward New Targets and Imaging Modalities
title_fullStr Scandium Radioisotopes—Toward New Targets and Imaging Modalities
title_full_unstemmed Scandium Radioisotopes—Toward New Targets and Imaging Modalities
title_short Scandium Radioisotopes—Toward New Targets and Imaging Modalities
title_sort scandium radioisotopes—toward new targets and imaging modalities
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675654/
https://www.ncbi.nlm.nih.gov/pubmed/38005390
http://dx.doi.org/10.3390/molecules28227668
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