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Brain Delivery of Cisplatin Using Microbubbles in Combination with Ultrasound as an Effective Therapy for Glioblastoma

Glioblastoma is a highly invasive and fatal disease. Temozolomide, a blood–brain barrier (BBB)-penetrant therapeutic agent currently used for glioblastoma, does not exhibit sufficient therapeutic effect. Cisplatin (CDDP), a versatile anticancer drug, is not considered a therapeutic option for gliobl...

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Detalles Bibliográficos
Autores principales: Hagiwara, Fumiko, Omata, Daiki, Munakata, Lisa, Kageyama, Saori, Maruyama, Kazuo, Kudo, Nobuki, Suzuki, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675703/
https://www.ncbi.nlm.nih.gov/pubmed/38004464
http://dx.doi.org/10.3390/ph16111599