Cargando…

New Insights into Polygenic Score–Lifestyle Interactions for Cardiometabolic Risk Factors from Genome-Wide Interaction Analyses

The relationship between lifestyles and cardiometabolic outcomes varies between individuals. In 382,275 UK Biobank Europeans, we investigate how lifestyles interact with polygenic scores (PGS) of cardiometabolic risk factors. We identify six interactions (PGS for body mass index with meat diet, phys...

Descripción completa

Detalles Bibliográficos
Autores principales:	D’Urso, Shannon, Hwang, Liang-Dar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675788/ https://www.ncbi.nlm.nih.gov/pubmed/38004209 http://dx.doi.org/10.3390/nu15224815

Ejemplares similares

Exploring polygenic contributors to subgroups of comorbid conditions in autism spectrum disorder
por: Klein, Louis, et al.
Publicado: (2022)

Interaction of obesity polygenic score with lifestyle risk factors in an electronic health record biobank
por: Dashti, Hassan S., et al.
Publicado: (2022)

Phenome-wide analysis of genome-wide polygenic scores
por: Krapohl, E, et al.
Publicado: (2016)

Clinical utility of polygenic scores for cardiometabolic disease in Arabs
por: Shim, Injeong, et al.
Publicado: (2023)

Associations of cardiometabolic polygenic risk scores with cardiovascular disease in African Americans
por: Tsegaselassie, Workalemahu, et al.
Publicado: (2023)

Comparison of Seven Healthy Lifestyle Scores Cardiometabolic Health: Age, Sex, and Lifestyle Interactions in the NutrIMDEA Web-Based Study
por: Ribot-Rodríguez, R., et al.
Publicado: (2023)

A flexible and parallelizable approach to genome‐wide polygenic risk scores
por: Newcombe, Paul J., et al.
Publicado: (2019)

Stability of polygenic scores across discovery genome-wide association studies
por: Schultz, Laura M., et al.
Publicado: (2022)

Derivation and Validation of Genome‐Wide Polygenic Score for Ischemic Heart Failure
por: Paranjpe, Ishan, et al.
Publicado: (2021)

Polygenic risk score, healthy lifestyles, and risk of incident depression
por: Cao, Zhi, et al.
Publicado: (2021)

Association of Polygenic Variants with Type 2 Diabetes Risk and Their Interaction with Lifestyles in Asians
por: Hur, Haeng Jeon, et al.
Publicado: (2022)

Polygenic risk score for Alzheimer’s disease and trajectories of cardiometabolic risk factors in children
por: Korologou-Linden, Roxanna, et al.
Publicado: (2019)

Interactions between Polygenic Scores and Environments: Methodological and Conceptual Challenges
por: Domingue, Benjamin W., et al.
Publicado: (2020)

Genome-Wide Polygenic Scores Predict Reading Performance Throughout the School Years
por: Selzam, Saskia, et al.
Publicado: (2017)

Genome-wide polygenic risk score for type 2 diabetes in Indian population
por: Pemmasani, Sandhya Kiran, et al.
Publicado: (2023)

Polygenic risk for obesity and its interaction with lifestyle and sociodemographic factors in European children and adolescents
por: Hüls, Anke, et al.
Publicado: (2021)

Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals
por: Huang, Qin Qin, et al.
Publicado: (2022)

Red cell distribution width and its polygenic score in relation to mortality and cardiometabolic outcomes
por: Pan, Jingxue, et al.
Publicado: (2023)

IPRS: Leveraging Gene-Environment Interaction to Reconstruct Polygenic Risk Score
por: Tang, Yingdan, et al.
Publicado: (2022)

Interaction of Cigarette Smoking and Polygenic Risk Score on Reduced Lung Function
por: Kim, Woori, et al.
Publicado: (2021)

Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies
por: Chatterjee, Nilanjan, et al.
Publicado: (2013)

Genome-wide polygenic scoring for a 14-year long-term average depression phenotype
por: Chang, Shun-Chiao, et al.
Publicado: (2014)

PRSet: Pathway-based polygenic risk score analyses and software
por: Choi, Shing Wan, et al.
Publicado: (2023)

Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians
por: Wünnemann, Florian, et al.
Publicado: (2019)

Genome-wide association study and polygenic risk score analysis of esketamine treatment response
por: Li, Qingqin S., et al.
Publicado: (2020)

An Improved Genome-Wide Polygenic Score Model for Predicting the Risk of Type 2 Diabetes
por: Liu, Wei, et al.
Publicado: (2021)

Improved prediction of fracture risk leveraging a genome-wide polygenic risk score
por: Lu, Tianyuan, et al.
Publicado: (2021)

The effect of heteroscedasticity on the prediction efficiency of genome-wide polygenic score for body mass index
por: Baek, Eun Ju, et al.
Publicado: (2022)

Development and Replication of a Genome-Wide Polygenic Risk Score for Chronic Back Pain
por: Tsepilov, Yakov A., et al.
Publicado: (2023)

The combined effect of lifestyle factors and polygenic scores on age at onset in Parkinson’s disease
por: Gabbert, Carolin, et al.
Publicado: (2023)

Genome-Wide Polygenic Risk Score for Predicting High Risk Glaucoma Individuals of Han Chinese Ancestry
por: Hsiao, Yu-Jer, et al.
Publicado: (2021)

Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures
por: Kapoor, M, et al.
Publicado: (2016)

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
por: Khera, Amit V., et al.
Publicado: (2018)

Cognitive Capacity Genome-Wide Polygenic Scores Identify Individuals with Slower Cognitive Decline in Aging
por: Joo, Yoonjung Yoonie, et al.
Publicado: (2022)

Contribution of Genome-Wide Polygenic Score to Risk of Coronary Artery Disease in Childhood Cancer Survivors
por: Sapkota, Yadav, et al.
Publicado: (2022)

Getting the Most Out of Your Genome-Wide Association Study Using Polygenic Risk Scores
por: Maggioncalda, Emily, et al.
Publicado: (2023)

Little Contribution of Genome-Wide Gene-Diet Interactions to Cardiometabolic Risk Factors in the UK Biobank
por: Westerman, Kenneth, et al.
Publicado: (2022)

Assessing the performance of European-derived cardiometabolic polygenic risk scores in South-Asians and their interplay with family history
por: Hassanin, Emadeldin, et al.
Publicado: (2023)

Gene Lifestyle Interactions With Relation to Obesity, Cardiometabolic, and Cardiovascular Traits Among South Asians
por: Ahmad, Shafqat, et al.
Publicado: (2019)

Influence of Genetic Interactions on Polygenic Prediction
por: Dai, Zhijun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ja9glra8sj69i65f6kmctd5mca