Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework †

This review summarizes achievements in the synthesis of 1,2-disubstituted adamantane derivatives by the construction of the tricyclic framework either by total synthesis or by ring expansion/contraction reactions of corresponding adamantane homologues. It is intended to complement reviews focusing o...

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Detalles Bibliográficos
Autores principales: Todd, Matthew, Hrdina, Radim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675813/
https://www.ncbi.nlm.nih.gov/pubmed/38005358
http://dx.doi.org/10.3390/molecules28227636
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author Todd, Matthew
Hrdina, Radim
author_facet Todd, Matthew
Hrdina, Radim
author_sort Todd, Matthew
collection PubMed
description This review summarizes achievements in the synthesis of 1,2-disubstituted adamantane derivatives by the construction of the tricyclic framework either by total synthesis or by ring expansion/contraction reactions of corresponding adamantane homologues. It is intended to complement reviews focusing on the preparation of 1,2-disubstituted derivatives by C–H functionalization methods.
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spelling pubmed-106758132023-11-16 Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework † Todd, Matthew Hrdina, Radim Molecules Review This review summarizes achievements in the synthesis of 1,2-disubstituted adamantane derivatives by the construction of the tricyclic framework either by total synthesis or by ring expansion/contraction reactions of corresponding adamantane homologues. It is intended to complement reviews focusing on the preparation of 1,2-disubstituted derivatives by C–H functionalization methods. MDPI 2023-11-16 /pmc/articles/PMC10675813/ /pubmed/38005358 http://dx.doi.org/10.3390/molecules28227636 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Todd, Matthew
Hrdina, Radim
Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework †
title Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework †
title_full Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework †
title_fullStr Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework †
title_full_unstemmed Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework †
title_short Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework †
title_sort synthesis of 1,2-disubstituted adamantane derivatives by construction of the adamantane framework †
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675813/
https://www.ncbi.nlm.nih.gov/pubmed/38005358
http://dx.doi.org/10.3390/molecules28227636
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