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Homogeneous liquid–liquid microextraction coupled with HPLC/DAD for determination of nirmatrelvir and ritonavir as COVID-19 combination therapy in human plasma

The study reports the development of a high-performance liquid chromatography/diode array detection method to measure the levels of nirmatrelvir and ritonavir in human plasma. These two antiviral medications are used for the treatment of COVID-19 and are marketed as Paxlovid(®). The method employed...

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Detalles Bibliográficos
Autores principales: Abdallah, Inas A., Hammad, Sherin F., Bedair, Alaa, Mansour, Fotouh R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675862/
https://www.ncbi.nlm.nih.gov/pubmed/38001530
http://dx.doi.org/10.1186/s13065-023-01080-4

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