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Colchicine prevents oxidative stress-induced endothelial cell senescence via blocking NF-κB and MAPKs: implications in vascular diseases

BACKGROUND: Smoking, alcohol abuse, and hypertension are – among others, potential risk factors for cardiovascular diseases. These risk factors generate oxidative stress and cause oxidative stress-induced DNA damage, resulting in cellular senescence and senescence-associated secretory phenotype (SAS...

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Detalles Bibliográficos
Autores principales: Zhou, Huakang, Khan, Dilaware, Hussain, Sajid Muhammad, Gerdes, Norbert, Hagenbeck, Carsten, Rana, Majeed, Cornelius, Jan Frederick, Muhammad, Sajjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675905/
https://www.ncbi.nlm.nih.gov/pubmed/38001470
http://dx.doi.org/10.1186/s12950-023-00366-7