Multi-omics study identifies that PICK1 deficiency causes male infertility by inhibiting vesicle trafficking in Sertoli cells

BACKGROUND: Infertility affects approximately 10–15% of reproductive-age men worldwide, and genetic causes play a role in one-third of cases. As a Bin-Amphiphysin-Rvs (BAR) domain protein, protein interacting with C-kinase 1 (PICK1) deficiency could lead to impairment of acrosome maturation. However...

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Detalles Bibliográficos
Autores principales: Jin, Jing, Li, Kaiqiang, Du, Yaoqiang, Gao, Fang, Wang, Zhen, Li, Weixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675906/
https://www.ncbi.nlm.nih.gov/pubmed/38001535
http://dx.doi.org/10.1186/s12958-023-01163-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675906/
https://www.ncbi.nlm.nih.gov/pubmed/38001535
http://dx.doi.org/10.1186/s12958-023-01163-w

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