Automatic generation of alloreactivity-reduced donor lymphocytes and hematopoietic stem cells from the same mobilized apheresis product

INTRODUCTION: In vitro or in vivo depletion of alloreactive T cells can facilitate haplo-identical hematopoietic stem cell transplantation (HSCT). Very satisfactory transplant outcomes were thus reported for TCRαβ/CD19-depleted hematopoietic stem/progenitor cell (HSPC) grafts. The current semi-autom...

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Detalles Bibliográficos
Autores principales: Wiercinska, E., Quade-Lyssy, P., Hümmer, C., Beifuß, J., Akarkach, K., Poppe, C., Olevska, V., Dzionek, J., Lahnor, H., Bosio, A., Papanikolaou, E., Bonig, Halvard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675913/
https://www.ncbi.nlm.nih.gov/pubmed/38007485
http://dx.doi.org/10.1186/s12967-023-04738-8

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