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Paneth cell-derived iNOS is required to maintain homeostasis in the intestinal stem cell niche

BACKGROUND: Mammalian intestinal epithelium constantly undergoes rapid self-renewal and regeneration sustained by intestinal stem cells (ISCs) within crypts. Inducible nitric oxide synthase (iNOS) is an important regulator in tissue homeostasis and inflammation. However, the functions of iNOS on ISC...

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Detalles Bibliográficos
Autores principales:	Huang, Lingxiao, Xu, Zhenni, Lei, Xudan, Huang, Yujun, Tu, Siyu, Xu, Lu, Xia, Jieying, Liu, Dengqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675917/ https://www.ncbi.nlm.nih.gov/pubmed/38007452 http://dx.doi.org/10.1186/s12967-023-04744-w

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