Cargando…

Evidence for widespread existence of functional novel and non-canonical human transcripts

BACKGROUND: Fraction of functional sequence in the human genome remains a key unresolved question in Biology and the subject of vigorous debate. While a plethora of studies have connected a significant fraction of human DNA to various biochemical processes, the classical definition of function requi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Dongyang, Tang, Lu, Zhou, Junjun, Wang, Fang, Cao, Huifen, Huang, Yu, Kapranov, Philipp
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675921/ https://www.ncbi.nlm.nih.gov/pubmed/38001496 http://dx.doi.org/10.1186/s12915-023-01753-5

Ejemplares similares

Evidence for Existence of Multiple Functional Human Small RNAs Derived from Transcripts of Protein-Coding Genes
por: Gao, Fan, et al.
Publicado: (2023)

Hotspots of single-strand DNA “breakome” are enriched at transcriptional start sites of genes
por: Cao, Huifen, et al.
Publicado: (2022)

Methods to Analyze the Non-Coding RNA Interactome—Recent Advances and Challenges
por: Cao, Huifen, et al.
Publicado: (2022)

A CRISPR/Cas13-based approach demonstrates biological relevance of vlinc class of long non-coding RNAs in anticancer drug response
por: Xu, Dongyang, et al.
Publicado: (2020)

Widespread occurrence of non-canonical transcription termination by human RNA polymerase III
por: Orioli, Andrea, et al.
Publicado: (2011)

Genome-Wide Profiling of Endogenous Single-Stranded DNA Using the SSiNGLe-P1 Method
por: Xu, Dongyang, et al.
Publicado: (2023)

Dark Matter RNA: Existence, Function, and Controversy
por: Kapranov, Philipp, et al.
Publicado: (2012)

Complex genomic patterns of abasic sites in mammalian DNA revealed by a high-resolution SSiNGLe-AP method
por: Cai, Ye, et al.
Publicado: (2022)

Widespread Non-Canonical Epigenetic Modifications in MMTV-NeuT Breast Cancer()()
por: Felts, Sara J., et al.
Publicado: (2015)

Lessons from discovery of true ADAR RNA editing sites in a human cell line
por: Wang, Fang, et al.
Publicado: (2023)

The canonical structure of the Grassmann models and existence of non-local currents
por: Maharana, J P
Publicado: (1986)

Very long intergenic non-coding (vlinc) RNAs directly regulate multiple genes in cis and trans
por: Cao, Huifen, et al.
Publicado: (2021)

From transcription start site to cell biology
por: Kapranov, Philipp
Publicado: (2009)

Evidence of widespread, independent sequence signature for transcription factor cobinding
por: Zhou, Manqi, et al.
Publicado: (2021)

Studying chromosome-wide transcriptional networks: new insights into disease?
por: Kapranov, Philipp
Publicado: (2009)

Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells
por: Cao, Huifen, et al.
Publicado: (2019)

Dynamic Patterns of Mammalian Mitochondrial DNA Replication Uncovered Using SSiNGLe-5′ES
por: Xu, Dongyang, et al.
Publicado: (2023)

Reverse-genetics studies of lncRNAs—what we have learnt and paths forward
por: Gao, Fan, et al.
Publicado: (2020)

Strand-specific RNA-seq reveals widespread occurrence of novel cis-natural antisense transcripts in rice
por: Lu, Tingting, et al.
Publicado: (2012)

Canonical and non-canonical functions of NLRP3
por: Accogli, Théo, et al.
Publicado: (2023)

Analysis of wheat SAGE tags reveals evidence for widespread antisense transcription
por: Poole, Rebecca L, et al.
Publicado: (2008)

Widespread evidence of cooperative DNA binding by transcription factors in Drosophila development
por: Kazemian, Majid, et al.
Publicado: (2013)

Systematic identification of non-canonical transcription factor motifs
por: Chumpitaz-Diaz, Luis, et al.
Publicado: (2021)

Non-canonical vs. Canonical Functions of Heme Oxygenase-1 in Cancer
por: Jagadeesh, Achanta Sri Venakata, et al.
Publicado: (2022)

Canonical and novel non-canonical activities of the Holliday junction resolvase Yen1
por: Carreira, Raquel, et al.
Publicado: (2021)

Widespread Existence of Quorum Sensing Inhibitors in Marine Bacteria: Potential Drugs to Combat Pathogens with Novel Strategies
por: Zhao, Jing, et al.
Publicado: (2019)

Emerging Canonical and Non-Canonical Roles of Granzyme B in Health and Disease
por: Tibbs, Ellis, et al.
Publicado: (2022)

Canonical and non-canonical JAK/STAT transcriptional targets may be involved in distinct and overlapping cellular processes
por: Tsurumi, Amy, et al.
Publicado: (2017)

Non-canonical behaviour in canonical theories
por: Jackiw, R
Publicado: (1969)

Canonical and Non-canonical Reelin Signaling
por: Bock, Hans H., et al.
Publicado: (2016)

Non-canonical transcriptional regulation of heme oxygenase in Aedes aegypti
por: Bottino-Rojas, Vanessa, et al.
Publicado: (2019)

Editorial: Regulatory T Cell Heterogeneity: Canonical and Non-Canonical Functions
por: Sefik, Esen, et al.
Publicado: (2021)

OR2801 Novel Cis-Regulatory Mechanisms Of Lhb Transcription By Non-Coding RNAs And Non-Canonical DNA Structures
por: Refael, Tal, et al.
Publicado: (2023)

Editorial: Recent Progresses of Non-coding RNAs in Biological and Medical Research
por: Zheng, Yun, et al.
Publicado: (2020)

Novel perspectives on non-canonical inflammasome activation
por: Diamond, Catherine Emma, et al.
Publicado: (2015)

Odor Characteristics of Novel Non-Canonical Terpenes
por: Sommer, Svenja, et al.
Publicado: (2022)

Widespread concerns still exist in relation to discrimination towards women and girls and FGM
por: Gerry, Felicity, et al.
Publicado: (2021)

Widespread Antisense Transcription in Escherichia coli
por: Dornenburg, James E., et al.
Publicado: (2010)

Canonical and Non-canonical Genomic Imprinting in Rodents
por: Kobayashi, Hisato
Publicado: (2021)

The Role of Non-canonical and Canonical Inflammasomes in Inflammaging
por: Cyr, Brianna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0g03budp82bnb5s55agoftoecf