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Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [(64)Cu][Cu(ATSM)] PET and proteomic studies
BACKGROUND: Brain metastases (BM) are the most frequent malignant brain tumors. The aim of this study was to characterize the tumor microenvironment (TME) of BM and particularly hypoxia and redox state, known to play a role in tumor growth and treatment resistance with multimodal PET and MRI imaging...
Autores principales: | Fantin, Jade, Toutain, Jérôme, Pérès, Elodie A., Bernay, Benoit, Mehani, Sarina Maya, Helaine, Charly, Bourgeois, Mickael, Brunaud, Carole, Chazalviel, Laurent, Pontin, Julien, Corroyer-Dulmont, Aurélien, Valable, Samuel, Cherel, Michel, Bernaudin, Myriam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676347/ https://www.ncbi.nlm.nih.gov/pubmed/38006431 http://dx.doi.org/10.1186/s13550-023-01052-8 |
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