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Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [(64)Cu][Cu(ATSM)] PET and proteomic studies

BACKGROUND: Brain metastases (BM) are the most frequent malignant brain tumors. The aim of this study was to characterize the tumor microenvironment (TME) of BM and particularly hypoxia and redox state, known to play a role in tumor growth and treatment resistance with multimodal PET and MRI imaging...

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Detalles Bibliográficos
Autores principales: Fantin, Jade, Toutain, Jérôme, Pérès, Elodie A., Bernay, Benoit, Mehani, Sarina Maya, Helaine, Charly, Bourgeois, Mickael, Brunaud, Carole, Chazalviel, Laurent, Pontin, Julien, Corroyer-Dulmont, Aurélien, Valable, Samuel, Cherel, Michel, Bernaudin, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676347/
https://www.ncbi.nlm.nih.gov/pubmed/38006431
http://dx.doi.org/10.1186/s13550-023-01052-8

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