Negative modulation of mitochondrial calcium uniporter complex protects neurons against ferroptosis

Ferroptosis is an iron- and reactive oxygen species (ROS)-dependent form of regulated cell death, that has been implicated in Alzheimer’s disease and Parkinson’s disease. Inhibition of cystine/glutamate antiporter could lead to mitochondrial fragmentation, mitochondrial calcium ([Ca(2+)](m)) overloa...

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Detalles Bibliográficos
Autores principales: Marmolejo-Garza, Alejandro, Krabbendam, Inge E., Luu, Minh Danh Anh, Brouwer, Famke, Trombetta-Lima, Marina, Unal, Osman, O’Connor, Shane J., Majerníková, Naďa, Elzinga, Carolina R. S., Mammucari, Cristina, Schmidt, Martina, Madesh, Muniswamy, Boddeke, Erik, Dolga, Amalia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676387/
https://www.ncbi.nlm.nih.gov/pubmed/38007529
http://dx.doi.org/10.1038/s41419-023-06290-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676387/
https://www.ncbi.nlm.nih.gov/pubmed/38007529
http://dx.doi.org/10.1038/s41419-023-06290-1

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