Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide

Cigarette smoking impairs the lung innate immune response making smokers more susceptible to infections and severe symptoms. Dysregulation of cell death is emerging as a key player in chronic inflammatory conditions. We have recently reported that short exposure of human monocyte-derived macrophages...

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Detalles Bibliográficos
Autores principales: Cristaldi, Marta, Buscetta, Marco, Cimino, Maura, La Mensa, Agnese, Giuffrè, Maria Rita, Fiore, Luigi, Carcione, Claudia, Bucchieri, Fabio, Rappa, Francesca, Coronnello, Claudia, Sciaraffa, Nicolina, Amato, Santina, Aronica, Tommaso Silvano, Lo Iacono, Giovanna, Bertani, Alessandro, Pace, Elisabetta, Cipollina, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676397/
https://www.ncbi.nlm.nih.gov/pubmed/38007509
http://dx.doi.org/10.1038/s41419-023-06318-6

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