VirB, a transcriptional activator of virulence in Shigella flexneri, uses CTP as a cofactor

VirB is a transcriptional activator of virulence in the gram-negative bacterium Shigella flexneri encoded by the large invasion plasmid, pINV. It counteracts the transcriptional silencing by the nucleoid structuring protein, H-NS. Mutations in virB lead to loss of virulence. Studies suggested that V...

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Detalles Bibliográficos
Autores principales: Antar, Hammam, Gruber, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676424/
https://www.ncbi.nlm.nih.gov/pubmed/38007587
http://dx.doi.org/10.1038/s42003-023-05590-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676424/
https://www.ncbi.nlm.nih.gov/pubmed/38007587
http://dx.doi.org/10.1038/s42003-023-05590-8

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