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VirB, a transcriptional activator of virulence in Shigella flexneri, uses CTP as a cofactor
VirB is a transcriptional activator of virulence in the gram-negative bacterium Shigella flexneri encoded by the large invasion plasmid, pINV. It counteracts the transcriptional silencing by the nucleoid structuring protein, H-NS. Mutations in virB lead to loss of virulence. Studies suggested that V...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676424/ https://www.ncbi.nlm.nih.gov/pubmed/38007587 http://dx.doi.org/10.1038/s42003-023-05590-8 |