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The Prevalence of MYD88 L265P and TNFAIP3 Mutations and Their Correlations with Clinico-Hematological Profile in Egyptian Patients with Diffuse Large B Cell Lymphoma

BACKGROUND: Activated B-cell–like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) is characterized by chronic active B-cell receptor signaling and a constitutive activation of the NF-KB pathway. MYD88 L265P mutation occurs as a driving force of NF-KB overactivity in ABC-DLBCL. Nonetheless, in...

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Detalles Bibliográficos
Autores principales: Elbaz, Osama, Shaat, Rana M., Abd El Ghaffar, Hasan A., Shamaa, Sameh, Abdel-Masseih, Hanaa M., Anber, Nahla, Mortada, Metwaly Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676502/
https://www.ncbi.nlm.nih.gov/pubmed/37505783
http://dx.doi.org/10.31557/APJCP.2023.24.7.2485