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Hypoglycemia and Cardiovascular Disease: Exploring the Connections

It has long been known that administering insulin or insulin secretagogues to treat diabetes has the unfavorable side effect of hypoglycemia. Because hypoglycemia can disrupt normal brain function, it can have a profound impact on people's lives. Studies have shown a connection between hypoglyc...

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Detalles Bibliográficos
Autores principales: Akhaury, Kishan, Wanjari, Anil, Sinha, Arya Harshyt, Kumar, Mayank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676516/
https://www.ncbi.nlm.nih.gov/pubmed/38022365
http://dx.doi.org/10.7759/cureus.47784
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author Akhaury, Kishan
Wanjari, Anil
Sinha, Arya Harshyt
Kumar, Mayank
author_facet Akhaury, Kishan
Wanjari, Anil
Sinha, Arya Harshyt
Kumar, Mayank
author_sort Akhaury, Kishan
collection PubMed
description It has long been known that administering insulin or insulin secretagogues to treat diabetes has the unfavorable side effect of hypoglycemia. Because hypoglycemia can disrupt normal brain function, it can have a profound impact on people's lives. Studies have shown a connection between hypoglycemia and a higher risk of death and cardiovascular disease. Through experimental studies, numerous potential reasons for the start of cardiovascular events have been discovered. In addition, studies on people have demonstrated that hypoglycemia can result in ventricular arrhythmias. According to recent studies, a number of factors may affect the relationship between hypoglycemia, cardiovascular events, and mortality. Confounding factors may explain the apparent correlation, at least in part. People with comorbidities may experience more hypoglycemia, increasing their risk of mortality. Those who have type 1 or type 2 diabetes, however, seem to be more susceptible to the negative effects of hypoglycemia on the cardiovascular system. When choosing appropriate glucose-lowering treatments and setting glycemic objectives with patients, clinicians should be aware of this risk.
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spelling pubmed-106765162023-10-27 Hypoglycemia and Cardiovascular Disease: Exploring the Connections Akhaury, Kishan Wanjari, Anil Sinha, Arya Harshyt Kumar, Mayank Cureus Endocrinology/Diabetes/Metabolism It has long been known that administering insulin or insulin secretagogues to treat diabetes has the unfavorable side effect of hypoglycemia. Because hypoglycemia can disrupt normal brain function, it can have a profound impact on people's lives. Studies have shown a connection between hypoglycemia and a higher risk of death and cardiovascular disease. Through experimental studies, numerous potential reasons for the start of cardiovascular events have been discovered. In addition, studies on people have demonstrated that hypoglycemia can result in ventricular arrhythmias. According to recent studies, a number of factors may affect the relationship between hypoglycemia, cardiovascular events, and mortality. Confounding factors may explain the apparent correlation, at least in part. People with comorbidities may experience more hypoglycemia, increasing their risk of mortality. Those who have type 1 or type 2 diabetes, however, seem to be more susceptible to the negative effects of hypoglycemia on the cardiovascular system. When choosing appropriate glucose-lowering treatments and setting glycemic objectives with patients, clinicians should be aware of this risk. Cureus 2023-10-27 /pmc/articles/PMC10676516/ /pubmed/38022365 http://dx.doi.org/10.7759/cureus.47784 Text en Copyright © 2023, Akhaury et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Akhaury, Kishan
Wanjari, Anil
Sinha, Arya Harshyt
Kumar, Mayank
Hypoglycemia and Cardiovascular Disease: Exploring the Connections
title Hypoglycemia and Cardiovascular Disease: Exploring the Connections
title_full Hypoglycemia and Cardiovascular Disease: Exploring the Connections
title_fullStr Hypoglycemia and Cardiovascular Disease: Exploring the Connections
title_full_unstemmed Hypoglycemia and Cardiovascular Disease: Exploring the Connections
title_short Hypoglycemia and Cardiovascular Disease: Exploring the Connections
title_sort hypoglycemia and cardiovascular disease: exploring the connections
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676516/
https://www.ncbi.nlm.nih.gov/pubmed/38022365
http://dx.doi.org/10.7759/cureus.47784
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