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Enhanced annotation of CD45RA to distinguish T cell subsets in single-cell RNA-seq via machine learning

MOTIVATION: T cell heterogeneity presents a challenge for accurate cell identification, understanding their inherent plasticity, and characterizing their critical role in adaptive immunity. Immunologists have traditionally employed techniques such as flow cytometry to identify T cell subtypes based...

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Detalles Bibliográficos
Autores principales: Ran, Ran, Brubaker, Douglas K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676521/
https://www.ncbi.nlm.nih.gov/pubmed/38023329
http://dx.doi.org/10.1093/bioadv/vbad159