CRISPR/Cas9 Ablated BCL11A Unveils the Genes with Possible Role of Globin Switching

PURPOSE: Fetal hemoglobin (HbF) upregulation is a mitigating factor in β-hemoglobinopathies therapy like β-thalassemia and sickle cell diseases. Finding molecular mechanisms and the key regulators responsible for globin switching could be helpful to develop effective ways to HbF upregulation. In our...

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Detalles Bibliográficos
Autores principales: Movahedi Motlagh, Fatemeh, Soleimanpour‐Lichaei, Hamid Reza, Shamsara, Mehdi, Etemadzadeh, Azadeh, Modarressi, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676543/
https://www.ncbi.nlm.nih.gov/pubmed/38022811
http://dx.doi.org/10.34172/apb.2023.074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676543/
https://www.ncbi.nlm.nih.gov/pubmed/38022811
http://dx.doi.org/10.34172/apb.2023.074

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