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Activating transcription factor (ATF) 6 upregulates cystathionine β synthetase (CBS) expression and hydrogen sulfide (H(2)S) synthesis to ameliorate liver metabolic damage

Activating transcription factor 6 (ATF6) is an endoplasmic reticulum stress responsive gene. We previously reported that conditional knockout of hepatic ATF6 exacerbated liver metabolic damage by repressing autophagy through mTOR pathway. However, the mechanism by which ATF6 influence liver metaboli...

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Detalles Bibliográficos
Autores principales: Dong, Bingzi, Sun, Ying, Cheng, Bingfei, Xue, Yu, Li, Wei, Sun, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676581/
https://www.ncbi.nlm.nih.gov/pubmed/38007457
http://dx.doi.org/10.1186/s40001-023-01520-w