Lung cDC1 and cDC2 dendritic cells priming naive CD8(+) T cells in situ prior to migration to draining lymph nodes

The current paradigm indicates that naive T cells are primed in secondary lymphoid organs. Here, we present evidence that intranasal administration of peptide antigens appended to nanofibers primes naive CD8(+) T cells in the lung independently and prior to priming in the draining mediastinal lymph...

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Detalles Bibliográficos
Autores principales: Si, Youhui, Wang, Yihan, Tian, Qiaomu, Wang, Qiang, Pollard, Jared M., Srivastava, Pramod K., Esser-Kahn, Aaron P., Collier, Joel H., Sperling, Anne I., Chong, Anita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676754/
https://www.ncbi.nlm.nih.gov/pubmed/37864794
http://dx.doi.org/10.1016/j.celrep.2023.113299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676754/
https://www.ncbi.nlm.nih.gov/pubmed/37864794
http://dx.doi.org/10.1016/j.celrep.2023.113299

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