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Lung cDC1 and cDC2 dendritic cells priming naive CD8(+) T cells in situ prior to migration to draining lymph nodes
The current paradigm indicates that naive T cells are primed in secondary lymphoid organs. Here, we present evidence that intranasal administration of peptide antigens appended to nanofibers primes naive CD8(+) T cells in the lung independently and prior to priming in the draining mediastinal lymph...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676754/ https://www.ncbi.nlm.nih.gov/pubmed/37864794 http://dx.doi.org/10.1016/j.celrep.2023.113299 |