POSTN Secretion by Extracellular Matrix Cancer-Associated Fibroblasts (eCAFs) Correlates with Poor ICB Response via Macrophage Chemotaxis Activation of Akt Signaling Pathway in Gastric Cancer

Immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, but its clinical benefit is limited in advanced gastric cancer (GC). Cancer-associated fibroblasts (CAFs) have been reported to be associated with ICB resistance, but the underlying mechanism has not been fully elucidated....

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Detalles Bibliográficos
Autores principales: You, Tingting, Tang, Hui, Wu, Wenjing, Gao, Jingxi, Li, Xuechun, Li, Ningning, Xu, Xiuxiu, Xing, Jiazhang, Ge, Hui, Xiao, Yi, Guo, Junchao, Wu, Bin, Li, Xiaoyi, Zhou, Liangrui, Zhao, Lin, Bai, Chunmei, Han, Qin, Sun, Zhao, Zhao, Robert Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676785/
https://www.ncbi.nlm.nih.gov/pubmed/37199594
http://dx.doi.org/10.14336/AD.2023.0503

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