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1155. Coadministration of Intranasal M2SR (M2-deficient Single Replication) Investigational Influenza Vaccine with Fluzone High Dose Induces Superior Immune Responses to Fluzone High Dose Alone in 65-85 Year Old Adults

BACKGROUND: Adults over age 65 years exhibit increased susceptibility to influenza viruses, accounting for 70-85% of annual influenza-related US fatalities. Licensed vaccines mainly induce serum humoral immunity and remain the primary method of influenza prevention, but vaccine effectiveness (VE) re...

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Detalles Bibliográficos
Autores principales: Eiden, Joseph, Fierro, Carlos, White, Alexander, Davis, Matthew, Rhee, Margaret, Turner, Mark, Murray, Bryan, Herber, Renee, Aitchison, Roger, Marshall, David, Moser, Michael, Bilsel, Pamuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676864/
http://dx.doi.org/10.1093/ofid/ofad500.995