305. PBMC-Derived Transcriptomic Signatures Accurately Discriminate Between Viral, Bacterial, and Fungal Infections and can be Translated to Real-World Human Infections

BACKGROUND: Analysis of host gene expression patterns (‘signatures’) can provide diagnostic information to determine the etiology of acute infection. In vitro experiments can be used to supplement our knowledge about these signatures. METHODS: We performed in vitro human peripheral blood mononuclear...

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Detalles Bibliográficos
Autores principales: Steinbrink, Julie M, Liu, Yiling, Henao, Ricardo, Tsalik, Ephraim L, Ginsburg, Geoffrey S, Ramsburg, Elizabeth, Woods, Christopher W, McClain, Micah T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676893/
http://dx.doi.org/10.1093/ofid/ofad500.377

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