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1744. Next generation sequencing (NGS) optimization of Oral Polio Vaccine samples

BACKGROUND: As wild poliovirus is eradicated, preventing circulation of vaccine-derived poliovirus is top priority. Our lab developed real-time multiplex PCR and deep sequencing methods to detect and characterize OPV strains directly from stool samples. This method requires gel purification of PCR p...

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Detalles Bibliográficos
Autores principales:	Carrington, Yuan J, Zhou, Frank, Tzou, Philip, Xiao, Mingze, Leary, Sean, Altamirano, Jonathan, Maldonado, Yvonne A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676901/ http://dx.doi.org/10.1093/ofid/ofad500.1575

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