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258. Clinical Rel Mutations in Staphylococcus aureus Primes Pathogen Expansion Under Nutrient Stress

BACKGROUND: Nutritional immunity is an important component of host defense whereby nutrients are sequestered to limit pathogen replication. The bacterial stringent response (SR) enables cells to modulate their growth, metabolism, and virulence in accordance with available nutrition. By analyzing wit...

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Detalles Bibliográficos
Autores principales: Chen, Edwin, Shaffer, Marla G, Bilodeau, Robert E, West, Raymond E, Oberly, Patrick J, Nolin, Thomas D, Culyba, Matthew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676952/
http://dx.doi.org/10.1093/ofid/ofad500.330