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2530. Pharmacokinetic-Pharmacodynamic (PK-PD) Target Attainment Analyses to Support Ceftobiprole Dose Selection for the Treatment of Patients with Acute Bacterial Skin and Skin Structure Infections (ABSSSI) and Community-Acquired Bacterial Pneumonia (CABP)
BACKGROUND: Ceftobiprole medocaril is an intravenously (IV) administered cephalosporin that is rapidly converted in vivo to the active moiety ceftobiprole. Ceftobiprole medocaril is being developed for the treatment of patients with ABSSSI and CABP. PK-PD target attainment analyses were performed to...
Autores principales: | Bhavnani, Sujata M, Hammel, Jeffrey P, Rinaldo, Anthony J, Smart, Jennifer, Litherland, Karine, Duncan, Leonard R, Jones, Mark E, Engelhardt, Marc, Ambrose, Paul G, Rubino, Christopher M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677075/ http://dx.doi.org/10.1093/ofid/ofad500.2148 |
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