2655. Phase 1 Safety and Immunogenicity Results of Two Investigational mRNA Vaccines, mRNA-1345, a Respiratory Syncytial Virus Vaccine, and mRNA-1653, a Human Metapneumovirus and Parainfluenza Virus Type 3 Combination Vaccine in Seropositive Young Children

BACKGROUND: Respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and parainfluenza virus type 3 (PIV3) are common respiratory illnesses in children. Two investigational vaccines, mRNA-1345, encoding the RSV prefusion stabilized F (preF) glycoprotein, and mRNA-1653, encoding the hMPV and...

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Autores principales: Snape, Matthew D, Ghamloush, Sabine Schnyder, Chen, Grace L, Dhar, Rakesh, Mithani, Runa, Righi, Vinicius, Morsy, Louie, Kapoor, Archana, Girard, Bethany, Asmar, Laila El, Shaw, Christine A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677146/
http://dx.doi.org/10.1093/ofid/ofad500.2266

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